Постинсультные когнитивные нарушения

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Постинсультные когнитивные нарушения

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Постинсультные когнитивные нарушения

Журнал "Медицинский совет. Неврология/Ревматология" № 18, 2018

В.А. Парфенов, С.В. Вербицкая, ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)

Когнитивные нарушения (КН) представляют одну из причин инвалидности больных, перенесших инсульт. Анализируются распространенность, механизмы развития, проявления, диагноз, лечение и профилактика постинсультных КН. Отмечается, что КН у больного, перенесшего инсульт, могут быть вызваны не только очаговым сосудистым поражением головного мозга, но  и наличием сопутствующих сосудистых и дегенеративных поражений. Представлены результаты собственного изучения в течение 5 лет КН у 350 больных, перенесших инсульт. Лечение и профилактика прогрессирования КН основаны на профилактике инсульта, нелекарственных и лекарственных методах улучшения когнитивных функций. Обсуждаются данные по использованию Церебролизина при инсульте, результаты двух последних метаанализов применения Церебролизина.

Cognitive impairment and dementia 

V.A. Parfenov, S.V. VerbitskayaSechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University) Post-stroke cognitive impairment

Cognitive impairment (CI) is one of the causes of acquired disability in post-stroke patients. The article presents an analysis of the prevalence, pathogenesis, manifestations, diagnosis, treatment and prevention of post-stroke CI. It is noted that CI can be caused not only by focal vascular brain damage, but also by the presence of concomitant vascular and degenerative lesions in stroke patients. The authors present the results of their own study of CI in 350 patients after stroke within 5 years. The treatment and prevention of CI progression are based on stroke prevention, non-pharmaceutical and pharmaceutical methods for improving cognitive functions. The article discusses data on the use of Cerebrolysin in post-stroke patients, the results of the two latter meta-analyses of Cerebrolysin use

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